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Hydrocodone 10-325

Hydrocodone is used to treat moderate to severe pain and as an antitussive to treat cough.[5] In one study comparing the potency of hydrocodone to that of oxycodone, it was found that it took 50% more hydrocodone to achieve the same degree of miosis (pupillary contraction). The investigators interpreted this to mean that oxycodone is about 50% more potent than hydrocodone.

However, in a study of emergency room patients with fractures, it was found that an equal amount of either drug provided about the same degree of pain relief, indicating that there is little practical difference between them when used for that purpose.[8] Some references state that the analgesic action of hydrocodone begins in 20–30 minutes and lasts about 4–8 hours.[9] The manufacturer’s information says onset of action is about 10–30 minutes and duration is about 4–6 hours.[10] Recommended dosing interval is 4–6 hours.

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Description

Hydrocodone is used to treat moderate to severe pain and as an antitussive to treat cough.[5] In one study comparing the potency of hydrocodone to that of oxycodone, it was found that it took 50% more hydrocodone to achieve the same degree of miosis (pupillary contraction). The investigators interpreted this to mean that oxycodone is about 50% more potent than hydrocodone.

However, in a study of emergency room patients with fractures, it was found that an equal amount of either drug provided about the same degree of pain relief, indicating that there is little practical difference between them when used for that purpose.[8] Some references state that the analgesic action of hydrocodone begins in 20–30 minutes and lasts about 4–8 hours.[9] The manufacturer’s information says onset of action is about 10–30 minutes and duration is about 4–6 hours.[10] Recommended dosing interval is 4–6 hours.

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30, 60, 90, 120, 150

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